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Potosi is a very small city located in the state of Missouri. With a population of 2,540 people and two associated neighborhoods, Potosi is the 239th largest community in Missouri.

As is often the case in a small city, Potosi doesn't have a public transportation system that people use for their commute.

The citizens of Potosi are slightly less educated than the national average of 21.84% for the average city or town: 13.97% of adults in Potosi have a bachelor's degree or advanced degree

The per capita income in Potosi in 2022 was $18,901, which is low income relative to Missouri and the nation. This equates to an annual income of $75,604 for a family of four.

Potosi is a somewhat ethnically-diverse city. The people who call Potosi home describe themselves as belonging to a variety of racial and ethnic groups. The greatest number of Potosi residents report their race to be White, followed by Black or African-American. Important ancestries of people in Potosi include German, Irish, English, French, and Scots-Irish.

The most common language spoken in Potosi is English. Other important languages spoken here include French and Tagalog.